Figure 1 | International Journal of Oral Science

Figure 1

From: Spatial signalling mediated by the transforming growth factor-β signalling pathway during tooth formation

Figure 1Figure 1

Morphological analysis of the transplants. (a) Schematic diagram of the reaggregated system. (b) Recombination from an E13.5 single-cell suspensions appeared as disordered tissue on an H&E-stained section. (c) At E14.5, the single-cell suspensions formed several epithelial pearls. (d, e) At E16.5 and E18.5, the single-cell suspensions exhibited tooth-like tissue. (f) At E13.5, the tooth germ transplants formed a boundary between the epithelial and mesenchymal tissue. (g–i) And at E14.5, E16.5 and E18.5, the tooth germ formed tooth-like tissue. Scale bar for b and f: 50 μm; for c and g: 100 μm; and for d, e, h and i: 200 μm. E, embryonic day.

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