Table 2 Effect of estrogen modulation on abscesses and sepsis in anti-IL-1-treated female mice

From: Interleukin-1 and estrogen protect against disseminating dentoalveolar infections

Treatment

Control IgG

Anti-IL-1α/β

Sham OVX (control)

0/11*

1/11

OVX

2/11

7/10

OVX+E2 implant

0/11

2/11†

  1. IgG, immunoglobulin G; IL, interleukin; OVX, ovariectomy.
  2. Frequency of abscesses/sepsis.
  3. P<0.01 by χ2.
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