Figure 2 | International Journal of Oral Science

Figure 2

From: The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells

Figure 2

S. mitis shows AhR-dependent induction of pro-inflammatory mediators CXCL2 and CXCL8. Fold changes in the transcription of chemoattractants CXCL1 (a), CXCL2 (b) and CXCL8 (c) were determined by real-time RT-PCR in human primary oral keratinocytes exposed to live S. mitis for 90 min, with or without the AhR-specific inhibitor CH-223191 (n=4). Brackets marked with asterisks indicate statistically significance (ANOVA for repeated measures followed by Holm–Sidak adjustment for multiple comparisons; P<0.05). ANOVA, analysis of variance.

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