Figure 2
From: Doxycycline induces bone repair and changes in Wnt signalling

Representative photomicrographs of alveolar tissues after picrosirius red (PSR) staining (× 200), on the 7th and 14th post-tooth extraction days. The non-polarised (1st and 3rd columns) and polarised (2nd and 4th columns) light images are presented in the upper panel. The percentages of collagen fibres (lower panel) were determined from the polarised light images. (a) vs CTL, 7th day, P=0.000 5; (b) vs DOX10, 14th day, P=0.008 6; (c) vs CTL, 14th day, P=0.005 4; (d) vs DOX25, 14th day, P=0.031 8 (Two-way ANOVA and Tukey test for multiple comparisons). CTL, control; DOX10, doxycycline 10 mg·kg−1; DOX25, doxycycline 25 mg·kg−1.