Figure 1
From: The importance of a potential phosphorylation site in enamelin on enamel formation
The gross and microstructural defects of the enamel in ENAMRgsc514 mice. (a)–(c) At the gross level, the incisors of 7-week-old ENAMRgsc514 heterozygotes (Het) and homozygotes (Homo) displayed a chalky white color and rugged surfaces compared to the brownish smooth incisors of the wild type (WT) mice. (d)–(f) Backscattered SEM images of transversely cut lower jaws from 4-week-old mice. The jaws were cut at the position of the first lower molar. (g)–(i) Higher magnification of the transversely cut incisors in d–f. (j)–(l) Higher magnification of the boxed areas in g–i. The ENAMRgsc514 heterozygotes showed disorganized and hypomineralized enamel rods and interrods compared to the well-organized enamel microstructures in the WT mice; the ENAMRgsc514 homozygotes had no enamel on the dentin surface. DN, dentin, EN, enamel. Scale bars: 100 μm in g–i, 10 μm in j–l.
