Table 4 Over-/under-representation of bacterial families of OTUs differentially abundant between coral species, and congregated fold-change differences between healthy and diseased specimens of P. duerdeni and P. lutea (only families that were represented by at least five bacterial taxa were considered)

Bacterial family	OTU count ANOVA (total 1003)	OTU count PhyloChip (total 14 213)	Chi-square	P-value	Mean fold-change difference between healthy corals	Mean fold-change difference between diseased corals
More abundant in P. duerdeni
Aquabacteriaceae	12	310	3.9220	<0.05	1.92	1.87
Bacillaceae	38	264	16.9856	<0.0001	2.04	1.69
Bacteroidaceae	5	37	1.1628	ns	1.23	1.13
Burkholderiaceae	7	146	0.6845	ns	1.45	1.82
Clostridiaceae	13	176	0.0002	ns	2.08	1.52
Clostridiales Family XI. Incertae Sedis	6	101	0.0467	ns	2.25	1.99
Corynebacteriaceae	57	632	3.0345	ns	1.58	1.24
Flavobacteriaceae	27	629	6.4096	<0.05	2.64	1.93
Lachnospiraceae	138	1508	9.3097	<0.01	2.46	1.88
Lactobacillaceae	11	148	0.0000	ns	2.58	1.68
Pelagibacteraceae	8	258	5.0707	<0.05	1.58	1.83
Planococcaceae	5	32	1.8696	ns	2.62	2.31
Porphyromonadaceae	7	40	4.0121	< 0.05	1.3	1.68
Prevotellaceae	13	99	0.0010	ns	1.56	1.49
Pseudomonadaceae	24	797	18.3400	<0.0001	1.09	1.24
Rhodobacteraceae	10	355	8.3811	<0.01	2.64	1.59
Rhodospirillaceae	10	211	1.2334	ns	1.23	1.21
Rikenellaceae	7	46	2.7799	ns	1.91	1.71
Ruminococcaceae	57	616	3.7217	ns	2.79	2.13
Staphylococcaceae	14	323	2.9319	ns	1.67	1.41
Streptococcaceae	76	209	186.8096	<0.0001	3.18	2.28
unclassified	38	618	0.5811	ns	2.13	1.89
Veillonellaceae	10	112	0.2855	ns	2.57	2.25
More abundant in P. lutea
Comamonadaceae	101	903	20.4045	<0.0001	4.59	3.39
Desulfobacteraceae	6	88	0.0161	ns	1.28	1.09
Enterobacteriaceae	104	801	36.6887	<0.0001	2.66	2.08
Moraxellaceae	5	163	3.0366	ns	2.16	1.97
Propionibacteriaceae	6	65	0.1546	ns	1.57	1.09
Rikenellaceae II	32	332	2.5767	ns	1.53	1.27

Abbreviations: ANOVA, analysis of variance; NS, not significant; OTU, operational taxonomic unit.

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