Table 2 Nonparametric correlations between CRISPR spacer count and HGT measures

From: No evidence of inhibition of horizontal gene transfer by CRISPR–Cas on evolutionary timescales

Category

Spearman correlation coefficient (significance) all genomes

Spearman correlation genomes with 1 spacers

Bacteria

N

1237

532

 Prophages

0.186 (P<0.0001)

−0.127 (P=0.0033)

 Prophage proteins

0.176 (P<0.0001)

−0.166 (P=0.0001)

 Singleton fraction

−0.025 (P=0.383)

0.244 (P<0.0001

 Fraction of HGT (dinucleotide based)a

0.222 (P<0.0001)

0.138 (P=0.0323)

Archaea

N

114

96

 Singleton Fraction

−0.165 (P=0.08)

−0.211 (P=0.039)

 (dinucleotide-based)b

−0.013 (P=0.9358)

−0.049 (P=0.7715)

  1. Abbreviations: CRISPR, clustered, regularly, interspaced, short, palindromic repeats; HGT, horizontal gene transfer.
  2. aIn the dinucleotide-based analysis, N=327 and N=241, respectively.
  3. bIn the dinucleotide-based analysis, N=42 and N=38, respectively.