Figure 7
From: Bacteria isolated from lung modulate asthma susceptibility in mice
CNCM I 4969 and 4970 induce an intermediate inflammatory profile when given together. SPF mice were treated as described in Figure 4 but the two strains were inoculated together. (a) Mice were weighed daily. The growth curves are expressed as the mean±s.e.m. of individual weights (normalized to initial weight at day -2). (b) Serum and BAL responses were analyzed as described in Figures 5a and b. Data are shown individually and as the mean±s.e.m. (c) IL-5 was measured in RLN supernatants as described in Figure 5c. The RPMI±HDM values for the same mice are connected with a dotted line. (d) Lung histology was assessed as described in Figure 1. Lung sections were stained with hematoxylin–eosin–saffron (HES) or Periodic acid–Schiff and alcian blue (PAS/AB). One representative section (enlargement × 60) per group is shown. (a–d) All data represent one experiment with n=7–8 mice per group.
