Figure 4
Functional classification of ancestral gene families that were lost in the eubartonellae, but retained in B. apis and B. tamiae. (a) COG category distribution of B. apis and B. tamiae shared genes, which were lost in the eubartonellae. Of 456 gene families 387 that could be assigned to a COG category are shown in the bar graph. Categories were sorted according to the number of assigned gene families. Numbers indicate percentages. (b) Presence of amino acid and cofactor biosynthesis pathway genes in 22 Bartonella genomes and their inferred LCA. Only pathways for which genes were detected in the inferred genome of the LCA are shown (Supplementary Tables 4 and 5). Cofactors marked with asterisks indicate that some genes of the pathway were missing in the LCA and could not be identified in any of the analyzed genomes of contemporary Bartonella species. Intensity of blue coloring indicates number of genes present in each pathway according to the depicted scale.
