Figure 6
From: Cold adaptation regulated by cryptic prophage excision in Shewanella oneidensis
Proposed mechanism of cold adaptation regulated by prophage excision. The stable residence of CP4So in host genome is preferred at warm temperature, which ensures the function of tmRNA. H-NS silences CP4So excision by binding to the promoter of alpA and represses expression of alpA at warm temperature. Although at cold temperatures, due to the de-repression of H-NS to alpA, CP4So excises and the excision leads to the formation of subpopulation (0.1–3%) of prophage-free cells with increased attached biofilm formation for the entire population.
