Figure 5
From: Diabetes-associated microbiota in fa/fa rats is modified by Roux-en-Y gastric bypass
Cecal microbiota transplant. (a) Bacterial diversity as shown by diversity box plots obtained from alpha rarefaction measured by observed species. Data are shown as box and whiskers plots, indicating the median (thick line in the box), the 25th–75th percentile range (boxes), and the 1st–99th percentile range (whiskers). (b) Principal coordinate analysis (PCoA) plot using unweighted UniFrac distances of gut microbial communities obtained from sham and RYGB donors (n=2) and ileum and cecum of mice (n=9) colonized with cecal microbiota from sham-operated and RYGB-treated rats. Symbols represent data from individual rat donors and mouse recipients. (c) DNA copies of total bacteria per gram contents in the ileal and cecal microbiota of mice (n=9) colonized with cecal microbiota from sham-operated and RYGB-treated rats. (d) Oral glucose tolerance test curves and (e) fat percentage gain in mice (n=9) colonized with cecal microbiota from sham or RYGB rats. Data are mean±s.e.m. *P<0.05, **P<0.01 as indicated or versus RYGB recipient.
