Abstract
In the course of our screening for binding inhibitors of CD44 and hyaluronic acid, five active compounds, F-16438 A, B, E, F and G were found and isolated from the cultured broth of a fungal strain, Gloeoporus dichrous SANK 30502. The structures of these compounds except for F-16438 G were elucidated by physico-chemical and spectral data to be new compounds related to caloporoside; F-16438 G was identified to be the 6′-malonylated derivative of caloporoside.
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Hirota-takahata, Y., Harada, H., Tanaka, I. et al. F-16438s, Novel Binding Inhibitors of CD44 and Hyaluronic Acid. J Antibiot 59, 777–784 (2006). https://doi.org/10.1038/ja.2006.102
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DOI: https://doi.org/10.1038/ja.2006.102
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