Abstract
A new ultraviolet-A (UV-A) protecting benzodiazepine alkaloid, circumdatin I (1), along with the previously described circumdatin C (2) and circumdatin G (3), have been isolated from the mycelium of a marine-derived fungus of the genus Exophiala. The structures of the three circumdatins were assigned on the basis of physicochemical evidence. The absolute stereochemistry of 1 was determined by comparison of optical rotation and CD experiments with those of 2 and 3.
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Zhang, D., Yang, X., Kang, J. et al. Circumdatin I, a New Ultraviolet-A Protecting Benzodiazepine Alkaloid from a Marine Isolate of the Fungus Exophiala. J Antibiot 61, 40–42 (2008). https://doi.org/10.1038/ja.2008.108
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DOI: https://doi.org/10.1038/ja.2008.108
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