Abstract
Two new aromatic alkaloids, designated citrinamides A and B, were isolated from the culture broth of penicillium sp. FKI–1938 by solvent extraction, silica gel column chromatography and HPLC. Their structures were elucidated by spectroscopic analysis, including NMR and amino acid analysis. Citrinamides A and B showed moderate potentiation of miconazole activity against Candida albicans.
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Fukuda, T., Hasegawa, Y., Sakabe, Y. et al. Citrinamides, New Potentiators of Antifungal Miconazole Activity, Produced by Penicillium sp. FKI-1938. J Antibiot 61, 550–555 (2008). https://doi.org/10.1038/ja.2008.73
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DOI: https://doi.org/10.1038/ja.2008.73
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