Table 2 Comparative in vitro activity of compound PM2409 (2), Kocurin (1), vancomycin and metronidazole against C. difficile
From: In vitro antibacterial activities of a thiazolyl peptide antibiotic PM2409
Supplemented brucella agar a | Wilkins–Chalgren agar a | ||||||
---|---|---|---|---|---|---|---|
Strain | Compound | MIC range b | MIC 50 | MIC 90 | MIC range b | MIC 50 | MIC 90 |
C. difficile | PM2409 (2) | 0.5–1 | 0.5 | 1 | 0.25 | 0.25 | 0.25 |
Kocurin (1) | 0.12–0.25 | 0.25 | 0.5 | 0.03–0.25 | 0.12 | 0.25 | |
Vancomycin | 1–4 | 1 | 4 | 0.5–4 | 1 | 2 | |
Metronidazole | 0.25–0.5 | 0.25 | 0.5 | 0.25–2 | 0.5 | 1 |