Figure 2
From: A model to predict anti-tuberculosis activity: value proposition for marine microorganisms
Score plot of mycobacteria-active natural products sourced from marine microbes and TB drugs. (a) PC1 (molecular size) versus PC2 (molecular aromaticity) versus PC3 (molecular lipophilicity) for sets of 28 synthetic TB drugs and candidates (black empty circle) and 11 nature-derived TB drugs and candidates (black filled circle) and (b) PC1 (molecular size) versus PC2 (molecular aromaticity) versus PC3 (molecular lipophilicity) for sets of 39 TB drugs and candidates (black) and 60 mycobacteria-active natural products from marine microbes (gray). TB, tuberculosis.
