Table 1 Study schedule.
From: Bisphenol A and phthalate metabolite urinary concentrations: Daily and across pregnancy variability
Study time period | Early pregnancy (Prior to 20 weeks) | 2nd Trimester (24–28 weeks) | 3rd Trimester (32–36 weeks) | Delivery | 2–3 Months post-partum | |
|---|---|---|---|---|---|---|
T1a | T1b | T2 | T3 | T4 | T5 | |
Day of the week | Weekday | Weekend day | Either | Either | Either | |
Type of sample | All voids collected throughout a 24 h period as multiple spot urine samples | All voids collected throughout a 24 h period as multiple spot urine samples | One spot urine sample | One spot urine sample | One spot urine sample | |
Chemical analysis Part I | X | X | X | X | X | |
Sample sizea | 64 | 66 | 70 | 71 | 63 | |
No. samples | 522 (median of 8 per participant) | 534 (median 8 per participant) | 70 | 71 | 63 | |
Chemical analysis Part II | X | X | ||||
Sample sizeb | 31 | 31 | ||||
No. samples | 270 (median=9 per participant) | 272 (median=9 per participant) | ||||