Summary
Plasma AT-III exhibits a microheterogeneous form with pIs distributed over a narrow pH range by analytical agarose gel isoelectric focusing followed by immunofixation. Three new variants, each of which was the heterozygous state between the common and each variant components, were observed in a total 370 samples from unrelated healthy donors. These variants have at least normal activities of the thrombin inactivation in the presence of heparin, and their immunological antigen concentrations in plasma are in the normal range.
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Kera, Y., Yamasawa, K. & Komura, S. Phenotypic variation of human antithrombin III in normal plasma: Detection by isoelectric focusing. Jap J Human Genet 28, 249–253 (1983). https://doi.org/10.1007/BF01876787
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DOI: https://doi.org/10.1007/BF01876787
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