Figure 4 | Journal of Human Genetics

Figure 4

From: Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis

Figure 4

Mapping of aberrations at Xp11.23-p11.22 detected in families MRF91 and MR67H. Disease-associated and copy-number-sensitive genes (not drawn to scale) are described by chevrons. Gaps in the genome assembly, segmental duplications (Dups) are shown. Filled bars and gray bars indicate >99% similarity and 90–99% similarity, respectively, in segmental duplications. High-density oligonucleotide array (Agilent 244K) revealed an ∼1.15-Mb duplication at Xp11.23 in MRF91 (filled bar) and an ∼2.67-Mb deletion at Xp11.23-p11.22 in MR67H (open bar).

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