Table 1 Total number of predicted SNVs after a targeted sequencing

From: Polymorphisms in DCDC2 and S100B associate with developmental dyslexia

Platform

Samples (pools)

Overlapping SNVs

Variants in ROI a

Validated SNVs (Finnish/German sample)

SOLiD4

10

 

282

92/89

5500xl

9b

 

291

 

SOLiD4+5500xl

10+9b

236

310

85c

  1. Abbreviations: ROI, regions of interest; SNV, single-nucleotide variants.
  2. aVariants predicted by the CRISP algorithm located in the captured ROI.
  3. b90% of the libraries were sequenced by using the 5500xl platform.
  4. cOverlapping validated SNVs from both sequencing runs (SOLiD4+5500xl) by using CRISP variant prediction.
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