Table 1 Clinical characteristics of six cases presented

From: Change in the pattern of adrenal venous sampling over time in patients with primary aldosteronism

 

Case 1

Case 2

Case 3

Case 4

Case 5

Case 6

Age

47

53

57

52

46

59

Sex

Male

Female

Female

Male

Female

Male

Race

White

White

AA

White

White

White

Duration of HTN (years)

15

15

27

2

16

20

Serum K (mmol l−1)

3.7

4.0

3.8

3.1

3.1

3.1

CO2 (mmol l−1)

30

22

30

31

31

26

PAC (ng 100ml−1)

29.3

29.0

53.2

32.8

N/A

10.4

PRA (ng ml−1 hr−1)

0.6

0.5

0.1

0.2

N/A

0.44

PAC/PRA

48.8

58.0

532

164

N/A

24

Imaging modality

CT

CT

MRI

CT

CT

CT

Side of mass on imaging

Left

Right

Right

Left

Right

Left

Size of mass on imaging (cm)

0.5

1.3

2.0

1.2

1.4

2.4

1st AVS A/C ratio

      

 IVC

2.23

2.80

1.69

2.21

4.08

0.71

 R

10.6

12.3

2.00

1.72

3.19

0.24

 L

3.18

4.79

6.71

4.74

1.27

0.64

LI

3.34

2.56

3.35

2.75

2.50

2.70

2nd AVS A/C ratio

 IVC

1.87

1.86

4.35

3.93

3.23

1.05

 R

11.5

4.63

7.60

1.18

5.09

0.77

 L

7.21

2.98

29.3

10.3

1.10

2.79

LI

1.59

1.55

3.86

8.67

4.63

3.62

Interval (months)

36

31

14

14

7

31

Year of first AVS

2003

2005

2006

2004

2003

2005

BP at presentation (mm Hg)

132/94

120/82

160/80

142/94

171/109

170/86

No. of meds at presentation

4

2

4

1

2

5

Adrenalectomy

No

No

Yes

Yes

Yes

Yes

BP post-operatively (mm Hg)

145/89 (2 mo)

124/84 (1 mo)

138/90 (14 mo)

110/80 (2 wk)

No. of meds postoperatively

4

0

2

4

Serum K post-operatively (mmol l−1)

4.4

4.2

4.8

4.6

  1. Abbreviations: AA, African American; AVS, adrenal venous sampling; A/C ratio, aldosterone to cortisol ratio; CO2, carbon dioxide; CT, computed tomography; HTN, hypertension; IVC, inferior vena cava; K, potassium; LI, lateralization index (please see text for definition); L, left adrenal vein; N/A, not available; MRI, magnetic resonance imaging; PAC, plasma aldosterone concentration; PRA, plasma renin activity; R, right adrenal vein. The LI of the 1st and 2nd AVS are shown in bold for comparison.