Table 2 Baseline blood pressure and changes in clinic and ABPM of SBP/DBP after 24 weeks of treatment
LS mean (s.e.) | AZL-M 40 | AZL-M 80 | RAM 10 | |||
|---|---|---|---|---|---|---|
SBP | DBP | SBP | DBP | SBP | DBP | |
Baseline clinic BP | 160.9±0.5 | 94.8±0.5 | 161.5±0.5 | 95.7±0.5 | 161.4±0.5 | 94.6±0.5 |
Change from BL to week 24 | −20.6±0.9 | −10.2±0.6 | −21.2±0.9 | −10.5±0.6 | −12.2±0.9 | −4.9±0.6 |
Baseline 24-h mean ABPM | 140.7±1.0 | 86.4±0.8 | 139.5±1.0 | 86.0±0.7 | 141.0±1.0 | 86.7±0.8 |
Change from BL to week 24 | ||||||
24-h mean | −12.7±1.0 | −8.0±0.7 | −12.3±1.0 | −8.3±0.6 | −7.8±1.0 | −5.3±0.7 |
Mean daytime (0600–2200 hours) | −12.6±1.0 | −8.2±0.7 | −12.4±1.0 | −8.5±0.7 | −8.1±1.1 | −5.6±0.7 |
Mean nighttime (0000–0600 hours) | −12.8±1.1 | −7.4±0.8 | −12.7±1.1 | −8.2±0.8 | −6.9±1.1 | −4.4±0.8 |
Mean trough (22–24 h) | −15.6±1.2 | −10.2±0.9 | −14.9±1.2 | −9.9±0.9 | −6.7±1.2 | −4.5±0.9 |
