Table 4 Baseline predictors of the 6-month responses of office and 24-h systolic blood pressures to renal denervation in 109 patients

From: Blood pressure changes after renal denervation at 10 European expert centers

 

Blood pressure control

Improved blood pressure control

No decrease in blood pressure

Office blood pressure, mm Hg

 Number of patients in category (%)

25 (22.9)

65 (59.6)

25 (22.9)

 Baseline (+10 mm Hg)

0.78 (0.61–0.99)†

1.36 (1.10–1.69)‡

0.71 (0.54–0.93)‡

 Being female (0,1)

1.12 (0.30–4.00)

1.00 (0.31–3.28)

1.41 (0.33–5.99)

 Age (+10 years)

0.81 (0.52–1.27)

0.72 (0.47–1.10)

1.36 (0.85–2.16)

 Body mass index (+5 kg m−2)

0.62 (0.34–1.14)

1.20 (0.70–2.07)

0.62 (0.31–1.25)

 Serum creatinine (+20 μmol l−1)

1.01 (0.66–1.54)

0.61 (0.39–0.97)†

1.80 (1.11–2.91)†

 Having diabetes (0,1)

2.19 (0.64–7.49)

1.38 (0.42–4.53)

0.46 (0.11–1.97)

 Cardiovascular disease (0, 1)

1.08 (0.29–3.95)

5.39 (1.41–20.6)†

0.59 (0.14–2.56)

24-h blood pressure, mm Hg

 Number of patients in category (%)

16 (14.7)

34 (31.2)

38 (34.9)

 Baseline (+10 mm Hg)

0.49 (0.39–0.79)‡

1.31 (0.99–1.73)*

0.90 (0.69–1.17)

 Being female (0,1)

0.73 (0.15–3.55)

0.52 (0.17–1.64)

1.80 (0.59–5.55)

 Age (+10 years)

0.78 (0.44–1.40)

1.35 (0.88–2.07)

0.68 (0.45–1.03)*

 Body mass index (+5 kg m−2)

0.72 (0.36–1.47)

0.66 (0.40–1.09)*

1.19 (0.73–1.94)

 Serum creatinine (+20 μmol l−1)

0.53 (0.26–1.09)*

0.60 (0.36–1.00)†

1.66 (1.11–2.49)‡

 Having diabetes (0,1)

1.27 (0.28–5.72)

1.43 (0.45–4.56)

1.36 (0.46–4.04)

 Cardiovascular disease (0, 1)

3.39 (0.69–16.7)

0.49 (0.14–1.70)

0.60 (0.18–1.96)

  1. Values are independent odds ratios with 95% confidence interval. All estimates were adjusted for the baseline systolic blood pressure and for all other predictors considered (see Table 3). Reaching control was achieving a systolic pressure <140 mm Hg or <130 mm Hg on office or 24-h ambulatory measurement, respectively. Reaching improved control was a decrease in the office or 24-h systolic pressure by 10 mm Hg. No decrease was a systolic pressure at 6 months equal to or higher than the baseline value.
  2. Significance of the odds ratios: *P0.10; †P0.05; ‡P0.01.