Table 1 Baseline characteristics (full analysis set)

From: Efficacy and safety of the dual L- and T-type calcium channel blocker, ACT-280778: a proof-of-concept study in patients with mild-to-moderate essential hypertension

 

Placebo,

N=53

ACT-280778,

N=52

Amlodipine,

N=54

Sex, female

 n (%)

28 (52.8)

22 (42.3)

26 (48.1)

Age, years

 Mean (s.d.)

55.8 (10.1)

58.9 (10.3)

56.6 (10.9)

 Median (range)

57 (28–73)

61 (26–74)

58 (30–74)

Caucasian/white

 n (%)

53 (100)

52 (100)

54 (100)

Weight, kg

 Mean (s.d.)

80.5 (13.2)

81.4 (12.6)

81.8 (15.3)

Height, cm

 Mean (s.d.)

169.7 (9.4)

168.8 (9.4)

170.2 (9.7)

BMI, kg m −2

 Mean (s.d.)

27.9 (3.7)

28.6 (3.4)

28.1 (3.6)

SiDBP, mm Hg

 Mean (s.d.)

98.0 (3.8)

98.7 (3.3)

98.8 (3.3)

SiSBP, mm Hg

 Mean (s.d.)

148.6 (9.9)

150.9 (9.2)

150.1 (9.3)

  1. Abbreviations: BMI, body mass index; SiDBP, sitting diastolic blood pressure; SiSBP, sitting systolic blood pressure.
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