Table 2 Multivariable analysis of the association of systolic blood pressure (SBP) phenotypes with other patient characteristics

Variables	Mean day SBP		Mean night SBP		Day–night decline in SBP
	Beta (s.e.)	P-value	Beta (s.e.)	P-value	Beta (s.e.)	P-value	Beta (s.e.) ^a	P-value^a
Age	1.418 (0.404)	4.4x10^-4	−0.281 (0.376)	0.454	1.175 (0.236)	6.5x10⁻⁷	0.915 (0.225)	4.68 × 10⁻⁵
Gender^b	−4.627 (0.762)	1.2x10⁻⁹	−3.218 (0.709)	5.6x10⁻⁶	−0.582 (0.445)	0.191	0.277 (0.427)	0.517
Body mass index	1.423 (0.324)	1.2x10 ⁻⁵	1.034 (0.300)	0.001	0.164 (0.188)	0.383	−0.100 (0.179)	0.578
Total cholesterol	0.772 (0.839)	0.358	−1.287 (0.775)	0.097	1.556 (0.485)	0.001	1.426 (0.459)	0.002
LDL cholesterol	0.673 (0.811)	0.406	1.499 (0.748)	0.045	−0.771 (0.468)	0.099	−0.916 (0.442)	0.038
Triglyceride	0.556 (0.307)	0.071	0.933 (0.285)	0.001	−0.354 (0.178)	0.047	−0.465 (0.169)	0.006
Plasma urate	1.314 (0.388)	0.001	1.149 (0.359)	0.001	−0.043 (0.225)	0.848	−0.287 (0.214)	0.180
Blood glucose	0.29 (0.266)	0.274	0.436 (0.247)	0.078	−0.147 (0.155)	0.343	−0.201 (0.147)	0.172
eGFR	0.69 (0.373)	0.064	0.509 (0.346)	0.14	0.079 (0.216)	0.715	−0.059 (0.205)	0.775
24-h Urine sodium	0.356 (0.287)	0.215	0.478 (0.266)	0.072	−0.113 (0.167)	0.498	−0.174 (0.158)	0.272
C-reactive protein	0.638 (0.261)	0.014	0.514 (0.243)	0.034	0.022 (0.153)	0.888	−0.096 (0.145)	0.506
Alcohol units	1.314 (0.289)	5.3x10⁻⁶	0.813 (0.268)	0.002	0.221 (0.168)	0.189	−0.015 (0.160)	0.924
Current smoker	−0.357 (0.27)	0.186	−1.302 (0.25)	1.9x10⁻⁷	0.811 (0.157)	2.2x10⁻⁷	0.874 (0.148)	3.79 × 10⁻⁹

Abbreviations: eGFR, estimated glomerular filtration rate; LDL cholesterol, low-density lipoprotein cholesterol.
All beta values are given per standard deviation (s.d.) change in the variable, with a negative beta representing an inverse correlation. Note that the beta values for the day–night decline in BP is a % while those for mean day and night SBP are in mm Hg.
^aAdditionally adjusted for mean daytime SBP.
^bGender is females compared to males.

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