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Clinical outcome of umbilical artery catheter-related thrombosis—a cohort study

Journal of Perinatology volume 32, pages 933–940 (2012)Cite this article

Subjects

Abstract

Objective:

To reveal the incidence of umbilical artery catheter-related thrombosis (UACRT), the associated risk factors and the natural history of clot formation and regression.

Study Design:

A prospective cohort study. An umbilical artery catheter was inserted in 61 infants, who were evaluated and followed by serial duplex ultrasound studies for the development of UACRT, renal artery resistance index (RI) and clot resolution. Maternal and infant clinical variables were correlated with the characteristics of thrombi.

Result:

Nineteen infants developed UACRT, all resolved spontaneously without sequella; most had maximal length at the first evaluation. No correlation was found between the thrombus length and time to resolution. The RI did not differ between the infants with and without UACRT. After adjusting for possible confounding, catheter days was the only covariate associated with UACRT.

Conclusion:

Asymptomatic UACRT in our cohort was a self-resolving disease; it was associated with catheter days and did not necessitate medical treatment.

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Author information

Author notes

  1. Z Ergaz and N Simanovsky: These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Neonatology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

    Z Ergaz, S Abu Leil, N Ofek-Shlomai & B Bar-Oz

  2. Department of Medical Imaging, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

    N Simanovsky & K Rozovsky

  3. Department of Pediatric Hematology/Oncology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

    S Revel-Vilk

Authors
  1. Z Ergaz
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  2. N Simanovsky
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  3. K Rozovsky
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  4. S Abu Leil
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  5. N Ofek-Shlomai
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  6. S Revel-Vilk
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  7. B Bar-Oz
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Correspondence to Z Ergaz.

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Ergaz, Z., Simanovsky, N., Rozovsky, K. et al. Clinical outcome of umbilical artery catheter-related thrombosis—a cohort study. J Perinatol 32, 933–940 (2012). https://doi.org/10.1038/jp.2012.4

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