Table 1 Univariate analysis for ECMO/death outcome for the entire study cohort consisting of early inhaled nitric oxide and control groups

From: Impact of early surfactant and inhaled nitric oxide therapies on outcomes in term/late preterm neonates with moderate hypoxic respiratory failure

Variable

All infants (n=299)

No ECMO/death (n=245)

ECMO/death (n=54)

P-value

Gestational age—mean (s.d.)

38.6 (2.0)

38.7 (2.0)

38.4 (2.0)

0.49

PaO2 response, torr

   

0.23

 Median (IQR)

37.0 (4.0, 89.0)

38.0 (6.0, 89.0)

22.0 (-3.0, 92.0)

 

 Mean (s.d.)

61.5 (85.1)

62.7 (82.6)

56.5 (95.8)

 

PaO2 response, n (%)

   

0.676

 Unknown

5

5 (100)

0

 

 <10 torr

100

83 (83)

17 (17)

 

 10–20 torr

39

30 (77)

9 (23)

 

 >20 torr

155

127 (82)

28 (18)

 

OI at enrollment, n (%)

   

0.031

 <20

180

155 (86)

25 (14)

 

 ⩾20

119

90 (76)

29 (24)

 

Diagnosis, n (%)

   

0.014

 Primary pulmonary hypertension

79

60 (76)

19 (24)

 

 RDS

52

49 (94)

3 (6)

 

 Perinatal aspiration

126

101 (80)

25 (20)

 

 Pneumonia/sepsis

41

35 (85)

6 (15)

 

 Lung hypoplasia

1

0

1 (100)

 

Prior use of surfactant, n (%)

   

0.008

 Yes

192

166 (86.5)

26 (13.5)

 

 No

107

79 (74)

28 (26)

 

Prior use of HFV, n (%)

   

0.88

 Yes

130

106 (81.5)

24 (18.5)

 

 No

169

139 (82)

30 (18)

 
  1. Abbreviations: ECMO, extracorporeal membrane oxygenation; HFV, high-frequency ventilation; IQR, interquartile range; OI, oxygenation index; RDS, respiratory distress syndrome.
  2. The n (%) for variables 3 to 7 in the table refer to the number and percent of neonates meeting the outcome specified for that column for each variable.
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