Table 2 Multivariate logistic regression analysis for ECMO/death outcome for the entire study cohort and for the individual treatment groups

From: Impact of early surfactant and inhaled nitric oxide therapies on outcomes in term/late preterm neonates with moderate hypoxic respiratory failure

Variable

Odds ratio (95% CI) for ECMO/death

P-value

Entire cohort

 Oxygenation index <20

0.52 (0.27–0.97)

0.04

 Surfactant use

0.47 (0.24–0.91)

0.03

Lung diseases relative to primary pulmonary hypertension

 RDS

0.22 (0.05–0.75)

0.03

 Perinatal aspiration

0.84 (0.41–1.75)

0.63

 Pneumonia/sepsis

0.49 (0.16–1.37)

0.20

Control group

 Surfactant use

0.27 (0.10–0.72)

0.01

Early iNO group

 iNO at OI <20 relative to iNO at OI 20–25

0.25 (0.08–0.67)

0.01

  1. Abbreviations: CI, confidence interval; ECMO, extracorporeal membrane oxygenation; iNO, inhaled nitric oxide; OI, oxygenation index; RDS, respiratory distress syndrome.