Table 1 Information and actions required to advance refinement within the scientific community

From: Improving quality of science through better animal welfare: the NC3Rs strategy

What we need to understand

What we need to do

The effects of research procedures on animal welfare

Be motivated to optimize the welfare of the animals in our care

How negative welfare states can be avoided or alleviated

Put the evidence base into practice, routinely and uniformly

How positive welfare states can be encouraged

Possess the necessary information, knowledge and skills

How welfare states, and hence the impact of refinements, can be reliably measured

Develop and share new ways of measuring and improving welfare

How animal welfare impacts on quality of science

Demonstrate publicly that welfare improvements are being made