Raske and colleagues studied the usefulness of intravenous ketamine and lidocaine infusions as adjuncts to inhalation anesthesia for sheep undergoing experimental stifle surgery. The authors intravenously injected ketamine and diazepam to induce anesthesia in the sheep and administered isoflurane in oxygen to maintain anesthesia. During surgery, some sheep received intravenous infusions of ketamine and lidocaine, whereas others did not. Sheep that received a meniscal implant without ketamine–lidocaine required ∼23% greater isoflurane concentrations than sheep that were given ketamine–lidocaine, suggesting that intravenous ketamine and lidocaine infusions decrease the amount of isoflurane required during orthopedic surgery on anesthetized sheep. See
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Since the 1970s, the use of goats in biomedical research has been increasing. Flaherty et al. discuss appropriate methods for induction of anesthetics, intubation and surgical maintenance of the goat during acute experimentation. They also describe Q fever and discuss measures that have been used to minimize zoonotic transmission of the Q fever pathogen to laboratory personnel. By increasing their knowledge of the goat and its handling and management during experimentation, the biomedical and veterinary research community will be able to more effectively use the goat for a variety of research studies. See
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