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  • Protocol Review
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Response to Protocol Review Scenario: Ask for Clarification

Lab Animal volume 32, pages 19–20 (2003)Cite this article

The question at hand is quite straightforward. Why should you have to use more dogs than necessary? However, there are several issues to address before the IACUC could give approval.

Even though the removal of mandibular lymph nodes would not be considered major surgery, it would be necessary to document that no adverse effects such as postoperative infection, drainage, or disfigurement have affected the dogs, and that in the process of the study each dog has not endured the burden of a lengthy recovery process. In addition, before the Committee allows Johnson to use these dogs, he should provide evidence, or at least a rationale, that the injection of radiolabeled cells, allergen exposure, and lymph node excision wouldn't affect the ear surgeries.

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References

  1. Carbone, L. Adoption of research animals. AWIC Newslett. 7 (1996/1997). http://www.nal.usda.gov/awic/newsletters/v7n3/7n3carbo .htm.

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  1. Goldberg is a Laboratory Animal Anesthesia Specialist in the Departments of Physical Therapy and Anatomy and Neurobiology and IACUC member at Virginia Commonwealth University/Medical College of Virginia (Richmond, VA).,

    Mary Ellen Goldberg VMT

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  1. Mary Ellen Goldberg VMT
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Goldberg, M. Response to Protocol Review Scenario: Ask for Clarification. Lab Anim 32, 19–20 (2003). https://doi.org/10.1038/laban0403-19b

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