Rodent housing space and animal care staff resources are often at a premium and the production of surplus animals raises ethical concerns. Hampshire and Davis discuss how, through careful consideration of the institution's research needs and the genetic makeup and breeding characteristics of actively maintained rodent strains, the veterinary staff can successfully manage transgenic mouse breeding programs to reduce uncontrolled breeding. See page 45
Cryopreserving mouse germ cells and embryos is a reliable way to free up facility space, while protecting valuable lines from loss due to environmental disasters, genetic drift, or infectious disease. Landel reviews the available cryopreservation techniques and presents considerations for setting up a cryopreservation facility. See page 50
