Figure 1 | Laboratory Investigation

Figure 1

From: Hypoxia response and VEGF-A expression in human proximal tubular epithelial cells in stable and progressive renal disease

Figure 1

Patient characteristics: Kidney function, proteinuria, degree of TAIF. (a) eGFR as indicator of kidney function calculated using the MDRD formula. Progressive patients showed worse renal function at the time of biopsy than stable patients (NS). Renal function declined further over time by more than 30%, or the patients reached ESRD. Median values and the 25th and 75th percentile are shown. (b) The degree of proteinuria as calculated using the protein–creatinine ratio is shown. At the time of biopsy, there was a trend toward higher proteinuria in the progressive group (P=0.08). During follow-up, the proteinuria declined significantly in the stable group (*P<0.0001), and the proteinuria was significantly lower in the stable than in the progressive patient cohort (**P=0.0005). Statistics were calculated using two-sided Mann–Whitney U-test with a CI of 95%. (c) The distribution of the degree of TAIF in stable and progressive patients is shown. The differences in distribution were not significant following a χ2 test.

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