Table 2 Up- and downregulated pathway members
Accession number | Gene name | Symbol | Pathway component | Fold change |
|---|---|---|---|---|
W88746 | CREB-binding protein (Rubinstein–Taybi syndrome) | CREBBP | CREBBP/p300 | 2.877 |
AA9765284 | PTK2B protein tyrosine kinase 2 beta | PTK2B | FAK | 2.539 |
AA709154 | Rho GTPase activating protein 1 | ARHGAP1 | Rac | 2.475 |
AA935529 | Nitric oxide synthase 1 (neuronal) | NOS1 | eNOS | 2.191 |
AA419268 | Phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta) | PIK3R2 | PI3K | 2.059 |
AA058828 | Fms-related tyrosine kinase 1 | FLT1 | VEGFR-2 | 1.945 |
W44318 | Mitogen-activated protein kinase 1 | MAPK1 | MEK/Erk | 1.913 |
AA293870 | Protein kinase C, epsilon | PRKCE | PKC | 1.866 |
AA485731 | Phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta) | PIK3R2 | PI3K | 1.814 |
W47003 | Hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | HIF1A | HIF1-a | 1.792 |
AA708437 | Phosphoinositide-3-kinase, catalytic, beta polypeptide | PIK3CB | PI3K | 1.765 |
W47196 | Aryl hydrocarbon receptor nuclear translocator | ARNT | HIF1-b | 1.748 |
H57180 | Phospholipase C, gamma 2 (phosphatidylinositol-specific) | PLCG2 | PLC-g | −1.750 |
AA608530 | FK506-binding protein 12-rapamycin-associated protein 1 | FRAP1 | mTOR | −1.764 |
AA630298 | PTK2 protein tyrosine kinase 2 | PTK2 | FAK | −1.798 |
R19956 | Vascular endothelial growth factor A | VEGFA | VEGFR-2 | −2.516 |
