Figure 3 | Laboratory Investigation

Figure 3

From: Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy

Figure 3

Maps of cystectomy specimens used for whole-organ genomic mapping. The distribution of in situ precursor lesions and TCC is shown in each individual cystectomy according to the histologic map code. Foci of carcinoma are outlined by a continuous red line. The histologic grade, pathogenetic subset, and stage for each focus of carcinoma are provided. The histologic map code is as follows: NU, normal urothelium; MD, mild dysplasia; MdD, moderate dysplasia; SD, severe dysplasia; CIS, carcinoma in situ; TCC, transitional cell carcinoma; LGIN, low-grade intraurothelial neoplasia; and HGIN, high-grade intraurothelial neoplasia.

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