Figure 2 | Laboratory Investigation

Figure 2

From: Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice

Figure 2

Colonic morphology of the WT and Muc2/IL-10DKO mice. Representative sections of the colon are depicted at 5 weeks (a–d, proximal colon; e–h, distal colon). (a and b, and e and f) Represent hematoxylin and eosin stainings whereas (c and d) and (g and h) represent AB-PAS stainings. (a and c, and e and g) Represent proximal colon and distal colon, respectively of the WT mice. (b and d, and f and h) Represent proximal colon and distal colon, respectively of the Muc2/IL-10DKO mice. The inset in (h) shows a close-up of goblet cells in the crypts of Muc2/IL-10DKO mice. The panels on the right-hand side with an asterisk represent a lower magnification of the distal colon.

Back to article page