Figure 1 | Laboratory Investigation

Figure 1

From: Induction of cytomegalovirus-infected labyrinthitis in newborn mice by lipopolysaccharide: a model for hearing loss in congenital CMV infection

Figure 1

Survival rate of newborn mice i.p. infected with MCMV in combination with i.c. injections of LPS or PBS. Newborn BALB/c mice were i.p. inoculated with MCMV (1 × 105 PFU) 2 days after birth. At 1 day before the infection, LPS (5 μg/5 μl) was injected into the bilateral brains. After MCMV infection, the same dose of LPS was injected into the other side of the brains alternatively three times or left without additional injection of LPS. Control mice were injected with PBS in the same way after i.p. infection with MCMV. Survival rates of mock-infected newborn mice that were injected one or four times with LPS are also shown.

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