Table 3 Continuous univariate analysis and 10 year dead of disease misclassification rates

From: Classification of renal cell carcinoma based on expression of VEGF and VEGF receptors in both tumor cells and endothelial cells

Marker

Hazard ratio

s.e.

P-value

Misclassification (95% CI)

Stage

    

 34 vs 12

7.82

0.27

0.00

0.24 (0.19–0.44)

Nuclear grade

    

 34 vs 12

5.24

0.25

0.00

0.26 (0.20–0.46)

VEGF

    

 Tumor

1.51

0.14

0.00

0.26 (0.21–0.32)

 Normal

0.70

0.14

0.01

0.24 (0.19–0.31)

 Difference

1.50

0.10

0.00

0.24 (0.18–0.29)

R1

    

 Tumor

1.62

0.17

0.01

0.26 (0.22–0.32)

 Normal

0.94

0.22

0.77

0.24 (0.19–0.29)

 Difference

1.39

0.14

0.02

0.24 (0.19–0.30)

R2

    

 Tumor

1.51

0.16

0.01

0.26 (0.21–0.31)

 Normal

0.64

0.23

0.05

0.24 (0.18–0.30)

 Difference

1.64

0.14

0.00

0.25 (0.19–0.30)

R3

    

 Tumor

1.64

0.22

0.02

0.26 (0.21–0.31)

 Normal

0.90

0.21

0.62

0.24 (0.20–0.30)

 Difference

1.53

0.19

0.03

0.24 (0.19–0.30)

R1

    

 Tumor vessel

1.13

0.17

0.46

0.26 (0.21–0.31)

 Normal vessel

1.00

0.15

1.00

0.24 (0.19–0.30)

 Difference

1.05

0.14

0.71

0.24 (0.19–0.30)

R2

    

 Tumor vessel

1.44

0.30

0.22

0.27 (0.21–0.32)

 Normal vessel

0.93

0.33

0.82

0.22 (0.17–0.29)

 Difference

1.38

0.30

0.28

0.24 (0.17–0.31)

R3

    

 Tumor vessel

1.51

0.17

0.02

0.26 (0.20–0.30)

 Normal vessel

1.41

0.20

0.08

0.24 (0.18–0.30)

 Difference

1.16

0.18

0.43

0.24 (0.19–0.30)

Tumor vessel area

0.87

0.06

0.04

0.26 (0.20–0.31)

Normal vessel area

0.87

0.13

0.29

0.24 (0.18–0.29)

Null model

   

0.26 (0.21–0.31)

  1. CI, confidence interval; s.e., standard error of the hazard ratio.
  2. Hazard ratios with P<0.05 are bolded.