Figure 2
From: Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice
Hepatic MAT genes mRNA levels during endotoxemia. (a) Steady-state mRNA levels of MAT1A, MAT2A, and MAT2β were determined by northern blot analysis as described in ‘Materials and Methods’. Membranes were sequentially probed with MAT1A, MAT2A, MAT2β, and 18S rRNA. (b) Summary of results expressed as % of control mRNA levels from three to eight animals per group. SAMe pretreatment group is labeled SAMe+LPS and SAMe post-treatment group is labeled LPS+SAMe. *P<0.005 vs control group, †P<0.05 vs LPS group.
