Figure 3 | Laboratory Investigation

Figure 3

From: The protective role of pregnane X receptor in lipopolysaccharide/D-galactosamine-induced acute liver injury

Figure 3

Activation of Stat3 by LPS/GalN is delayed in the livers of PXR-null mice. (a) Stat3 protein data. (b) Akt protein data. Mice were i.p. injected with LPS (100 μg/kg) and GalN (700 mg/kg) or saline (n=5/group/time point). Livers were removed at the time point as indicated. Liver proteins were immunoblotted with indicated antibodies and representative samples are shown in the figure.

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