Figure 7
Loss of PXR decreases the levels of anti-apoptotic proteins and alters the expression of proteins involved in autophagy pathways after LPS/GalN injection. (a) Anti-apoptotic protein data. (b) Autophagy protein data. Mice were i.p. injected with LPS (100 μg/kg) and GalN (700 mg/kg) or saline (n=5/group/time point). Livers were removed at the time point as indicated. Liver proteins were immunoblotted with indicated antibodies and representative samples are shown in the figure.
