Figure 4
From: Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice
Expression of hepatic stearoyl-Co enzyme A desaturase-1 (SCD-1) (a), and fatty acid synthase (FAS) (b) mRNA by qPCR in wt and Gclm null (ko) mice fed methionine-choline-sufficient (MCS) or methionine-choline-deficient (MCD) diet. *P<0.05 compared with wt MCS; #P<0.05 compared with ko MCS; $P<0.05 compared with wt MCD, for all groups, n=4–6 animals. Relative expression was determined by the ΔΔCt method as described in the Materials and Methods section, in which hepatic expression in wt, chow-fed, age-matched, male mice is 1.0.
