Table 1 Tumor-initiation activity of HNSCC cell lines

From: Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor

Cell lines

106 cells

3 × 105 cells

105 cells

3 × 104 cells

104 cells

3 × 103 cells

Detroit 562

5/5 (6.2)

5/5 (12.2)

5/5 (21)

4/5 (40.75)

4/5 (28.5)

0/5

Cal 27

5/5 (22.6)

5/5 (30.4)

4/5 (36.25)

5/5 (27.4)

4/5 (42.5)

0/5

FaDu

5/5 (15)

4/5 (18.25)

5/5 (26.6)

1/5 (45)

4/5 (50)

—

SCC25

—

5/5 (18.2)

5/5 (38.2)

1/5 (80)

—

—

SCC9

—

5/5 (59.2)

1/5 (28)

0/5

—

—

SCC15

2/4 (29)

1/4 (52)

0/5

0/5

—

—

  1. NOD/SCID mice were injected subcutaneously with varying numbers of cells from HNSCC cell lines. Mice were then monitored for 90 days to assess the time to onset of a palpable tumor. Data are presented as the number of mice with tumors/total number of mice injected (average days to onset of tumors).
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