Figure 4

Synovial tissue of the digits after prednisolone and sodium nedocromil therapy. Histological analysis showing the influx of neutrophils (a–c) and mast cells (d–f) within the digits joints. Neutrophils (arrows) and intact (arrowheads) or degranulated (open arrows) mast cells were obtained from untreated and mice administered with prednisolone or sodium nedocromil, on day 32 after CIA. Picrosirius and H&E-stain (a–c) and toluidine blue stains (d–f); scale bars: 10 μm.