Table 3 Neutrophils and mast cells migration profile after prednisolone and nedocromil therapy in the knees

From: An essential role for mast cells as modulators of neutrophils influx in collagen-induced arthritis in the mouse

 

Knee synovial tissue

Cell type

Untreated

Prednisolone

Nedocromil

Neutrophils

1,266±15

1,174±41***

54±4.8***

Intact mast cells

2.2±0.2

18.6±1.2***

0.7±0.1**

Degranulated mast cells

5.4±0.1

6.7±1.0

1.3±0.1***

  1. Data report the number of the specified cell type per mm2 as quantified in the knee synovial tissue of arthritic mice on day 32. Mice were either left untreated, or treated with Prednisolone (4 μmol/Kg) or Nedocromil (2 mg/Kg) from day 21 to day 32. Values are mean±s.e.m. of 5 mice pre group. **P<0.01 and ***P<0.001 vs untreated arthritic group.
Back to article page