Figure 6 | Laboratory Investigation

Figure 6

From: Endogenous sulfur dioxide protects against isoproterenol-induced myocardial injury and increases myocardial antioxidant capacity in rats

Figure 6

The changes in sulfur dioxide (SO2)/glutamic oxaloacetic transaminase (GOT) pathway in myocardial tissue of isoproterenol (ISO)-induced rats. In ISO-treated rats, myocardial sulfite content decreased compared with the controls, but it increased significantly in rats of ISO+SO2 group compared with that of ISO-treated rats, and in SO2 group it was markedly higher than that of controls (a). Myocardial GOT activity reduced in both ISO group and SO2 group compared with that of control rats, but it did not change in ISO+SO2 group compared with ISO group (b). GOT1 and GOT2 gene expressions downregulated in ISO-treated rats compared with control rats, but they did not differ between ISO+SO2 group and ISO group, and between SO2 group and control group (c). ##P<0.01 vs control group; #P<0.05, vs control group; and **P<0.01 vs ISO group.

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