Figure 5

Sorafenib treatment maintained the CD4 and CD8 cells in spleen and lymph nodes. A representative flow cytometric data showing the CD4+and CD8+ T-cells frequency of gated lymphocytes in spleen and lymph nodes from normal and HCC tumor-bearing mice treated with solvent or soarfenib. Numbers in the figures represent the percentage of fluorescence-positive cells in corresponding areas, representative data of three independent experiments.