Figure 2 | Laboratory Investigation

Figure 2

From: In vivo evidence for the role of RegI in gastric regeneration: transgenic overexpression of RegI accelerates the healing of experimental gastric ulcers

Figure 2

The ulcer index (UI) and expression of the transgene (rat regI gene) following exposure to water-immersion stress. (a) Adult gender-matched littermate pairs of Wt and Tg mice were exposed to 24 h of water-immersion stress and their stomachs were scored for cumulative length of gastric erosions (UI). Values for each pair of littermates (each connected by thin dashed line) and mean values for Wt mice (stippled box) and Tg mice (filled box) are presented. N=6 pairs. *P<0.05. (b) Total RNA was extracted from adult Tg stomachs with (24 h) or without (0 h) water-immersion stress and was analyzed using quantitative RT-PCR for expression of rat regI gene. Mean values±s.e.m. at each time point, normalized to the internal references (GAPDH). N=7 for 0 h, 12 for 24 h. *P<0.05.

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