Figure 1

Two-way unsupervised hierarchical clustering of laser capture microdissected (LCM) tumor epithelium, and patient-matched undissected material. Relative intensity values of 75 different signaling proteins obtained by reverse phase protein microarray were used. (a) LCM-procured cancer epithelium (CE-LCM); (b) patient-matched undissected whole tissue (WhT). Red indicates a high relative level of protein activation or expression, black for median value and green indicates low relative level of protein activation or expression.