Figure 3 | Laboratory Investigation

Figure 3

From: Protein pathway biomarker analysis of human cancer reveals requirement for upfront cellular-enrichment processing

Figure 3

Two-way scatter plots of Cox-2 and phosphorylated EGFR from LCM cancer epithelium vs patient-matched whole-tissue intensity values. Relative levels of Cox-2 (a) and pEGFR Y1148 (b) from RPMA data obtained from patient-matched undissected (y axis) and LCM-procured epithelium (x axis) were analyzed as a two-way scatter plot to compare the relative intensity values from those two inputs. Correlation of whole-tissue and LCM cancer epithelium in tissues is shown with different starting percentages of cancer epithelium in the tissue specimen: 20% tumor epithelium (top panel); 40% tumor epithelium (middle panel); and 60% tumor epithelium (bottom panel). Trend line along with R2 value is shown for each graph.

Back to article page